Specific isoforms of Drosophila shroom define spatial requirements for the induction of apical constriction
نویسندگان
چکیده
منابع مشابه
Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure
Apical constriction is an essential cell behavior during neural tube closure, but its underlying mechanisms are not fully understood. Lulu, or EPB4.1l5, is a FERM domain protein that has been implicated in apical constriction and actomyosin contractility in mouse embryos and cultured cells. Interference with the function of Lulu in Xenopus embryos by a specific antisense morpholino oligonucleot...
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15 صفحه اولShroom Induces Apical Constriction and Is Required for Hingepoint Formation during Neural Tube Closure
BACKGROUND The morphogenetic events of early vertebrate development generally involve the combined actions of several populations of cells, each engaged in a distinct behavior. Neural tube closure, for instance, involves apicobasal cell heightening, apical constriction at hingepoints, convergent extension of the midline, and pushing by the epidermis. Although a large number of genes are known t...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2010
ISSN: 1058-8388
DOI: 10.1002/dvdy.22408